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Research

DRNI Members Research is a list of ongoing and completed research carried out by DRNI members.
You can search via project type, disease, or Principal Investigator/Researcher name.

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Research type

  • Research project (88)
  • Research initiative (30)

Disease area

  • Dementia (including Alzheimer's Disease and other dementias) (49)
  • Motor Neurone Disease (14)
  • Parkinson's Disease and related disorders (13)
  • Neurodegenerative Disease (11)
  • Not specified (1)

Field of research

  • Basic/Discovery Research (37)
  • Clinical Research (26)
  • Social Research (8)
  • Public Health (6)
  • Connected Health (5)
  • Economic Research (4)
  • Brain Health (2)

An Examination of Virtual Reality Technology in the Training of Health Professionals and Carers.

Aim(s): To examine the impact of VR on the understanding of emotions, cognitions and behaviours for people living with dementia among health professionals and carers.

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An Exploration of Personhood in Dementia in Formal Care in Ireland

This project examined personhood in dementia within formal care provision and relationships in Ireland. The concept of personhood within the context of formal care was examined through three different lenses: formal care policy, formal care settings and formal care relationships. Each lens provides different insights and perspectives into personhood in dementia and at both the macro and micro level of formal care provision. The central research question was: How is personhood in dementia conceptualised, expressed, facilitated and actualised in formal care in Ireland?

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Analysis of tiRNA and tiRNA-protein Complexes and Development of tiRNAs as Therapeutics and Biomarkers in ALS and Epilepsy.

Project Aim(s): To perform a systematic analysis of tiRNA – protein complexes in ALS and Epilepsy models as well as samples from patients. 

 

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Applied Research Projects in Dementia: Towards Resilience in Family Caregiving for People with Dementia.

Project Aim(s): To develop and promote resilience in family carers of people with dementia.

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Applied Research Projects in Dementia: Validation of the Profile for Communication Abilities in Dementia (P-CAD).

Project Aim(s): To validate a cognitive communication assessment for people with dementia.

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Assessing Cognitive Communication Skills in Dementia: A Scoping Review.

Project Aim(s): To review published cognitive–communication assessments to determine what psychometrically sound assessments exist that are applicable to all people with dementia.

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Biological Resource Analysis to Identify New Mechanisms and Phenotypes in Neurodegenerative Diseases (BRAIN-MEND).

Project Aim(s): Our overall aim is to revise existing phenotypic classifications using pathways and network analyses to generate newer more biologically classifications based on causative mechanisms, potential new therapeutic drug targets and indications, treatment response profiles and clinical sub-phenotypes.

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BIOMARKAPD

BIOMARKAPD is a multi-national research project comprising 51 sites in 21 countries, including Ireland. This JPND (joint programme on neurodegenerative diseases) funded collaborative research project aims to develop optimally informative biomarkers for AD and PD and the harmonisation of their use. The Irish strand of BIOMARKPD aims to; standardise biomarker measurement and interpretation nationally; develop and make available a CSF test for ND biomarkers in AD and PD; Establish and sustain a registry of ND; and bring clarity to biomarker interpretation to support diagnosis.

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BIOMARKAPD (Biomarker Optimisation in AD & PD).

Alzheimer’s and Parkinson’s diseases (AD and PD) are the two most common neurodegenerative conditions. They cause major costs for society and suffering and death for millions of patients around the globe. In Europe, more than 8 million individuals have AD or PD. Current treatments are symptomatic but do not stop the underlying disease process. Using biomarkers, we can detect biochemical changes that show when neurons start to die. There are also biochemical tests for brain changes that are specific to AD and PD.

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BIOMARKPD

BIOMARKAPD is a multi-national research project comprising 51 sites in 21 countries, including Ireland. This JPND (Joint Programme on Neurodegenerative Diseases) funded collaborative research project aims to develop optimally informative biomarkers for AD and PD and the harmonisation of their use. The Irish strand of BIOMARKPD aims to; standardise biomarker measurement and interpretation nationally; develop and make available a CSF test for ND biomarkers in AD and PD; Establish and sustain a registry of ND; and bring clarity to biomarker interpretation to support diagnosis.

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  • Trinity College Dublin
  • University College Dublin
  • University College Cork
  • Dublin City University
  • National University of Ireland, Galway
  • The Alzheimer Society of Ireland
  • Health Research Board
  • Royal College of Surgeons in Ireland
  • University of Ulster
  • Queen's University Belfast
  • SPHeRE
  • Dementia - Understand Together
  • Trinity College Institute of Neuroscience
  • Engaging Dementia logo
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