We are a PhD training programme, linking together approximately 90 genomics data science group leaders based at five Irish institutions. Expertise within the group spans from statistical modeling and machine learning to the full range of application of genomics. Over the coming four years our research teams will be joined by 100 fully funded PhD students, recruited through this Centre.
Project Aim(s): To review published cognitive–communication assessments to determine what psychometrically sound assessments exist that are applicable to all people with dementia.
Project Aim(s):
(i) To Identify tiRNA/sncRNA fingerprints in AD, ALS, FTD and PD human disease i-neurons.
(ii) To determine if tiRNAs affect the survival of i-neurons from controls and ALS, PD and FTD models.
Project Aim(s): PD-MitoQUANT is an Innovative Medicines Initiative (IMI)Innovative Medicines Initiative (IMI) (www.imi.europa.eu) project that brings together academic experts, small and medium enterprises (SMEs), pharmaceutical companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA)European Federation of Pharmaceutical Industries and Associations (EFPIA) (www.efpia.eu) and patient advocacy organisation Parkinson’s UKParkinson’s UK (www.p
Project Aim(s): The aim of RNA-NEURO is to reveal the role of small non-coding RNAs in Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia, with a view to creating novel therapeutic strategies to treat these disorders.
Project Aim(s): To perform a systematic analysis of tiRNA – protein complexes in ALS and Epilepsy models as well as samples from patients.
Project Aim(s): To determine the effect(s) of CSF from Alzheimer's disease (AD) patients on cerebroids cultured healthy human iPSCs and to identify the mediator(s) of AD-CSF-mediated pathology.