The Dementia Services Information and Development Centre (DSIDC) is a National Centre for excellence in dementia. It provides educational courses and training days to staff providing services to people with dementia in many different care settings around the country. Their research activities focus on the development of timely, responsive and accessible interventions for people with dementia.
Research
DRNI Members Research is a list of ongoing and completed research carried out by DRNI members.
You can search via project type, disease, or Principal Investigator/Researcher name.
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Research type
Disease area
- Dementia (including Alzheimer's Disease and other dementias) (64)
- Parkinson's Disease and related disorders (16)
- Motor Neurone Disease (14)
- Neurodegenerative Disease (12)
- Lewy Body Dementia (2)
- Mild Cognitive Impairment (1)
- Not specified (1)
- Progressive Supranuclear Palsy and Corticobasal Syndrome (1)
- Young Onset Dementia (1)
Field of research
- Basic/Discovery Research (38)
- Clinical Research (27)
- Social Research (13)
- Public Health (6)
- Connected Health (5)
- Economic Research (4)
- Brain Health (3)
- Assistive technology for dementia (2)
- Clinical Research, Social Research, Connected Health, Economic Research (2)
- Health Services Research (2)
- Neurodegeneration (2)
- Social research, Economic research (2)
- Ageing and Nutrition research (1)
- Digital palliative care (1)
- Gait Speed and Technology (1)
- Nursing care (1)
- Occupational Therapy (1)
- Pharmacology & Therapeutics (1)
The Dementia Services Information and Development Centre (DSIDC) is a National Centre for excellence in dementia. It provides educational courses and training days to staff providing services to people with dementia in many different care settings around the country. Their research activities focus on the development of timely, responsive and accessible interventions for people with dementia.
Early, non-invasive, inexpensive biomarkers of Alzheimer’s Disease (AD) are much needed. Those with Down syndrome (DS) are the largest patient group at increased risk of AD. Evidence suggests that imaging the eye could be a non-invasive biomarker to screen for AD. However, there is limited information regarding ocular changes in DS. Our group was the first to image the lens in DS, revealing the presence of small ‘dot’ opacities in the lens in 54% of individuals with DS.
To assess whether targeting microglia, and consequently neuroinflammation, can restore impaired cognitive function in age and a model of Alzheimer’s disease.
Project Aim(s): This TCD led international network was set up to determine the prevalence of ALS/MND in Latin-America through collaborative work between Prof. Orla Hardiman and researchers in the various countries involved including Cuba, Uruguay and Chile.
- People are living longer, which means that more of us will get age-related illnesses such as dementia. Although Dementia usually affects people as they get older, it’s not a normal part of ageing. Many people don’t realise that Dementia is a terminal illness. Palliative Care aims to improve the quality of life of people and their families who are facing an incurable, life-limiting illness, such as dementia.
Progressive supranuclear palsy and corticobasal syndrome are progressive neurodegenerative diseases characterised by parkinsonian features (stiffness, slowness and tremor), balance difficulty with falls, abnormalities in the control of eye movements, difficulty with skilled movement (apraxia) and thinking problems. We currently do not have any information on the number of people in Ireland living with these conditions.
Parkinson’s disease is a debilitating disorder characterised by movement disorders, including tremor, cognitive dysfunction and non-motor impairments. It is the second most common age-related neurodegenerative disease with ~10 million sufferers worldwide, but the causes of tremor are poorly understood and treatment is wholly inadequate.
The STRIDES Study will explore the use of gait speed as both a vital sign and digital clinical biomarker in a diverse population of older adults. This research will focus on gait speed variability and its associated health implications, including cognitive decline, sarcopenia, frailty, and an increased risk of falls. One segment of the study will examine how changes in gait speed correlate with mild cognitive impairment (MCI), particularly looking at the prevalence of motor-cognitive risk syndrome which is diminished gait speed in the context of MCI.