Research
DRNI Members Research is a list of ongoing and completed research carried out by DRNI members.
You can search via project type, disease, or Principal Investigator/Researcher name.
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To assess whether targeting microglia, and consequently neuroinflammation, can restore impaired cognitive function in age and a model of Alzheimer’s disease.
Project Aim(s): This TCD led international network was set up to determine the prevalence of ALS/MND in Latin-America through collaborative work between Prof. Orla Hardiman and researchers in the various countries involved including Cuba, Uruguay and Chile.
Progressive supranuclear palsy and corticobasal syndrome are progressive neurodegenerative diseases characterised by parkinsonian features (stiffness, slowness and tremor), balance difficulty with falls, abnormalities in the control of eye movements, difficulty with skilled movement (apraxia) and thinking problems. We currently do not have any information on the number of people in Ireland living with these conditions.
The Irish Longitudinal Study on Ageing (TILDA) is a large-scale (n= approximately 8000 people), nationally representative study of people aged 50 and over in Ireland. It collects information on cognitive function in older adults in Ireland, based on objective measures of cognitive function and self-rated memory. It also provides important information on utilisation of health and social care services and on physical and behavioural health.
The Irish Longitudinal Study on Ageing (TILDA) is a large-scale (n= approximately 8000 people), nationally representative study of people aged 50 and over in Ireland. It collects information on cognitive function in older adults in Ireland, based on objective measures of cognitive function and self-rated memory. It also provides important information on utilisation of health and social care services and on physical and behavioural health
Project Aim(s): To execute preclinical testing of an HDAC3-specific inhibitor for disease prevention in Huntington's disease (HD).
The Trinity-Ulster-Department-of-Agriculture (TUDA) cohort is a unique and innovative resource for ageing research designed to assess the impact of nutritional, lifestyle, environmental and genetic factors on diseases of ageing, particularly in the prevention of cardiovascular disease, dementia and osteoporosis.