Project Aim(s): To examine how Ataxin-2 and Stress_Granule Modulatory Proteins function in ALS/FTD.
Research
DRNI Members Research is a list of ongoing and completed research carried out by DRNI members.
You can search via project type, disease, or Principal Investigator/Researcher name.
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Research type
Disease area
- Dementia (including Alzheimer's Disease and other dementias) (64)
- Parkinson's Disease and related disorders (16)
- Motor Neurone Disease (14)
- Neurodegenerative Disease (12)
- Lewy Body Dementia (2)
- Mild Cognitive Impairment (1)
- Not specified (1)
- Progressive Supranuclear Palsy and Corticobasal Syndrome (1)
- Young Onset Dementia (1)
Field of research
- Basic/Discovery Research (38)
- Clinical Research (27)
- Social Research (13)
- Public Health (6)
- Connected Health (5)
- Economic Research (4)
- Brain Health (3)
- Assistive technology for dementia (2)
- Clinical Research, Social Research, Connected Health, Economic Research (2)
- Health Services Research (2)
- Neurodegeneration (2)
- Social research, Economic research (2)
- Ageing and Nutrition research (1)
- Digital palliative care (1)
- Gait Speed and Technology (1)
- Nursing care (1)
- Occupational Therapy (1)
- Pharmacology & Therapeutics (1)
Persons with dementia should be at the centre of decision-making about their care including basic activities (e.g. feeding and dressing), advanced activities (e.g. finances and using transportation), and meaningful activities (e.g. social and recreational pastimes). However, there is limited involvement of people with dementia in design of technology to support their care.
Aim: to elucidate the direct and indirect pathways between social determinants and cognitive decline among older Irish adults, to further understand and identify potential points of intervention in the progression of cognitive decline.
Primary objectives:
To investigate the psychosocial effects of the introduction of an adaptive Irish Céilí dance group activity with people living with dementia and their carers.
α-Synuclein (α-Syn) pathology is inextricably linked to the pathogenesis of Parkinson’s disease (PD), yet we have very limited understanding why specific neuronal populations are vulnerable to α-Syn-related PD pathology while others are much more resistant.
Project Aim(s): To utilise brain organoids to investigate the aetiology of Alzheimer's disease.
1. What is the Person with Parkinson's community knowledge and experience of existing voice assisted technology?
2. What is the knowledge, experience and attitudes of Speech and Language Therapists towards voice assisted technology in practice?
Project Aim(s): The aim of RNA-NEURO is to reveal the role of small non-coding RNAs in Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia, with a view to creating novel therapeutic strategies to treat these disorders.
Project Aim(s): To determine the role of neuroinflammation in driving neurodegeneration.