The STRIDES Study will explore the use of gait speed as both a vital sign and digital clinical biomarker in a diverse population of older adults. This research will focus on gait speed variability and its associated health implications, including cognitive decline, sarcopenia, frailty, and an increased risk of falls. One segment of the study will examine how changes in gait speed correlate with mild cognitive impairment (MCI), particularly looking at the prevalence of motor-cognitive risk syndrome which is diminished gait speed in the context of MCI.
Tallaght University Hospital
Progressive supranuclear palsy and corticobasal syndrome are progressive neurodegenerative diseases characterised by parkinsonian features (stiffness, slowness and tremor), balance difficulty with falls, abnormalities in the control of eye movements, difficulty with skilled movement (apraxia) and thinking problems. We currently do not have any information on the number of people in Ireland living with these conditions.
To develop accessible best practice guidelines for post-diagnostic dementia supports for people with an intellectual disability in Ireland. The project aims to:
(1) examine the current landscape of post-diagnostic care at a national level;
(2) consider barriers to access;
(3) incorporate existing best practices; and
(4) give due consideration of the experiences and recommendations of people with an intellectual disability living with dementia and of their families/carers.
Increased knowledge about the pre-clinical and early clinical stages of Alzheimer's disease (AD) will be key in developing preventative strategies for the disease as well as development of therapeutic treatment strategies. In addition, this approach will contribute to the development of biomarkers for the early diagnosis of AD.