Alzheimer’s and Parkinson’s diseases (AD and PD) are the two most common neurodegenerative conditions. They cause major costs for society and suffering and death for millions of patients around the globe. In Europe, more than 8 million individuals have AD or PD. Current treatments are symptomatic but do not stop the underlying disease process. Using biomarkers, we can detect biochemical changes that show when neurons start to die. There are also biochemical tests for brain changes that are specific to AD and PD.
Trinity College Institute of Neuroscience
Project Aim(s): To determine the role of neuroinflammation in driving neurodegeneration.
Project Aim(s): The objective is the assessment of the impact of alterations of white matter tract integrity on effective connectivity in the neural network underpinning working memory. Using brain imaging data it will examine the associations between brain structure and function in young and older healthy participants and how normal ageing alters the relationship between structure and function.