1. What is the Person with Parkinson's community knowledge and experience of existing voice assisted technology?
2. What is the knowledge, experience and attitudes of Speech and Language Therapists towards voice assisted technology in practice?
DRNI Members Research is a list of ongoing and completed research carried out by DRNI members.
You can search via project type, disease, or Principal Investigator/Researcher name.
1. What is the Person with Parkinson's community knowledge and experience of existing voice assisted technology?
2. What is the knowledge, experience and attitudes of Speech and Language Therapists towards voice assisted technology in practice?
Project Aim(s): The aim of RNA-NEURO is to reveal the role of small non-coding RNAs in Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia, with a view to creating novel therapeutic strategies to treat these disorders.
Project Aim(s): To determine the role of neuroinflammation in driving neurodegeneration.
Early, non-invasive, inexpensive biomarkers of Alzheimer’s Disease (AD) are much needed. Those with Down syndrome (DS) are the largest patient group at increased risk of AD. Evidence suggests that imaging the eye could be a non-invasive biomarker to screen for AD. However, there is limited information regarding ocular changes in DS. Our group was the first to image the lens in DS, revealing the presence of small ‘dot’ opacities in the lens in 54% of individuals with DS.
To assess whether targeting microglia, and consequently neuroinflammation, can restore impaired cognitive function in age and a model of Alzheimer’s disease.
Project Aim(s): This TCD led international network was set up to determine the prevalence of ALS/MND in Latin-America through collaborative work between Prof. Orla Hardiman and researchers in the various countries involved including Cuba, Uruguay and Chile.
Progressive supranuclear palsy and corticobasal syndrome are progressive neurodegenerative diseases characterised by parkinsonian features (stiffness, slowness and tremor), balance difficulty with falls, abnormalities in the control of eye movements, difficulty with skilled movement (apraxia) and thinking problems. We currently do not have any information on the number of people in Ireland living with these conditions.
Project Aim(s): To execute preclinical testing of an HDAC3-specific inhibitor for disease prevention in Huntington's disease (HD).