Project Aim(s): To investigate bone morphogenetic protein 2 as a therapeutic for Parkinson's disease (PD).
Research
DRNI Members Research is a list of ongoing and completed research carried out by DRNI members.
You can search via project type, disease, or Principal Investigator/Researcher name.
Search
Research type
Disease area
Field of research
Project Aim(s): PD-MitoQUANT is an Innovative Medicines Initiative (IMI)Innovative Medicines Initiative (IMI) (www.imi.europa.eu) project that brings together academic experts, small and medium enterprises (SMEs), pharmaceutical companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA)European Federation of Pharmaceutical Industries and Associations (EFPIA) (www.efpia.eu) and patient advocacy organisation Parkinson’s UKParkinson’s UK (www.p
PMSMatTrain focuses on gaining a comprehensive understanding of the progressive phase of multiple sclerosis (PMS) from basics to translation, fully supported by eight beneficiaries (six research institutions and two SMEs).
Project Aim(s): To understand the genetic basis of ALS and to ultimately find a cure for this devastating, fatal neuromuscular disease, Project MinE aims to analyse the DNA of at least 15,000 ALS patients and 7,500 control subjects. The resulting 22,500 DNA profiles will be compared.
The overall aim of this research is to examine the effect of regular exercise on:
1) Adult hippocampal neurogenesis
2) Cognitive performance in hippocampus-dependent memory tasks
3) Microglial activation and neuroinflammatory profile using the transgenic mouse model of Alzheimer’s Disease [amyloid precursor protein (APP)SWE/presenilin-1 (PS-1)].
Project Aim(s): Development of optimally informative biomarkers for ALS, and establishment of stakeholder agreement regarding their use. This will be achieved by defining, validating and harmonizing optimal methodologies that can be reliably implemented within a pan-European framework program.
Project Aim(s): The development of neurotrophic factor therapy for Parkinson's disease (PD).
We are a PhD training programme, linking together approximately 90 genomics data science group leaders based at five Irish institutions. Expertise within the group spans from statistical modeling and machine learning to the full range of application of genomics. Over the coming four years our research teams will be joined by 100 fully funded PhD students, recruited through this Centre.
Project Aim(s): To examine how Ataxin-2 and Stress_Granule Modulatory Proteins function in ALS/FTD.