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No new Alzheimer's drug treatment had be licensed for 20 years until 2021, when the first Alzheimer's disease-modifying therapy (DMT) was licensed in the USA, giving hope of slowing/reversing the disease. Several new DMTs are expected. Unfortunately, offering DMTs in Ireland requires significant changes in Memory Clinic set-up, due to high drug costs and need for careful monitoring. Moreover, DMTs only work in people in early Alzheimer's, which is often unrecognized in Ireland. Thus, to ensure our health system is DMT ready, we will survey Irish residents and healthcare professionals regarding their perspectives on DMTs, since public views are critical to health developments. 

Additional Comments

​​​​​Papers published:

  • Leroi, I., Dolphin, H., Dinh, R., Foley, T., Kennelly, S., Kinchin, I., O'Caoimh, R., O’Dowd, S., O’Philbin, L., O’Reilly, S., Trepel, D., Timmons, S. (In press) Navigating the future of Alzheimer's care in Ireland - A service model for disease-modifying therapies in small and medium-sized healthcare systems BMC Health Services Research
  • Kinchin I, Walsh S, Dinh R, et al. Dissonance in the face of Alzheimer’s disease breakthroughs: clinician and lay stakeholder acceptance, concerns and willingness to pay for emerging disease-modifying therapies. The British Journal of Psychiatry. Published online 2024:1-7. doi:10.1192/bjp.2024.24
Disease area
Dementia (including Alzheimer's Disease and other dementias)
Field of research
Social research, Economic research
Principal Investigator/ Researcher Names
Professor Iracema Leroi
Professor Sean Kennelly
Professor Suzanne Timmons
Dr Irina Kinchin
Dr Ann Nolan
Alzheimer Society of Ireland - Dr Laura O'Philbin
HRB-CTN Dementia Trials Ireland - Laura Gibney
National Dementia Office - Dr Emer Begley
Global Brain Health Institute (GBHI) - Dr Sean O’Dowd
Institution
Trinity College Dublin
Funding body

Irish Research Council

Start date
Project completed
No
End/expected end date
Are you looking to Recruit Research Participants?
No
©2024 Dementia Research Network Ireland. Follow us on Twitter: @DRNIre