The overall aim of this research is to examine the effect of regular exercise on:
1) Adult hippocampal neurogenesis
2) Cognitive performance in hippocampus-dependent memory tasks
3) Microglial activation and neuroinflammatory profile using the transgenic mouse model of Alzheimer’s Disease [amyloid precursor protein (APP)SWE/presenilin-1 (PS-1)].
Disease area
Dementia (including Alzheimer's Disease and other dementias)
Field of research
Basic/Discovery Research
Principal Investigator/ Researcher Names
Dr. Áine Kelly
Sinéad Ryan
Institution
Trinity College Dublin
Funding body
Irish Research Council
Grant Awarded (€)
€91,790
Start date
Project completed
No
End/expected end date
Are you looking to Recruit Research Participants?
No