PD-MitoQUANT – A quantitative Approach towards the Characterisation of Mitochondrial Dysfunction in Parkinson's disease (PD).

Project Aim(s): PD-MitoQUANT is an Innovative Medicines Initiative (IMI)Innovative Medicines Initiative (IMI) (www.imi.europa.eu) project that brings together academic experts, small and medium enterprises (SMEs), pharmaceutical companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA)European Federation of Pharmaceutical Industries and Associations (EFPIA) (www.efpia.eu) and patient advocacy organisation Parkinson’s UKParkinson’s UK (www.parkinsons.org.uk).

The project aims to:

 

1) Improve our understanding of mitochondrial dysfunction in Parkinson’s  disease.

2) Identify and validate molecular drivers and mechanisms in Parkinson’s disease.

3) Discover innovative therapeutic targets that can be further progressed by the EFPIA partners in the future, and

4) Initiate a European research platform of excellence in PD that will continue beyond the project, providing long-term and sustainable progress in the understanding of mitochondrial dysfunction in PD, towards clinical application.

Principal Investigator/ Researcher Names

Prof. Jochen Prehn
Dr. Dana Bar-on (Project Leader - Teva Pharmaceutical Industries Ltd.)
Dr. Tina Stummann (Scientific Co-leader - H. Lundbeck A/S)
Dr. Olga Corti (Scientific Co-leader - Institut de Cerveau et de la Moelle Epiniere)
Dr. Orla Watters (ECR)
Dr. Niamh Connolly (ECR)

Disease Area

Parkinson's Disease and related disorders

Field of Research

Basic/Discovery Research

Institution

Centre National de la Recherche Scientifique (CNRS)
Consiglio Nationale delle Ricerche (CNR)
GeneXplain GmbH
German Center for Neurodegenerative Diseases (DZNE)
H. Lundbeck A/S
Institut du Cerveau et de la Moelle Epiniere (ICM)
Mimetas
Radboud University Nijmegen Medical Centre (RUMC)
Royal College of Surgeons Ireland (RCSI)
Teva Pharmaceutical Industries Ltd.
UCB S.A.
University College London (UCL)

Funding body

IMI2

Grant Awarded (€)

4,617,933.75

Start date

February 2020

End/expected end date

March 2019

Project Completed

No

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